Chronic pancreatitis is a persistent inflammation of the pancreas. The pancreas is a gland located behind the stomach. It secretes digestive enzymes and the hormones insulin and glucagon. The persistent inflammation leads to the destruction of the functioning tissue in the pancreas. The pancreatic digestive enzymes are not produced, resulting in an inability to properly digest and absorb fat in the diet. There is also a decrease in the production of insulin. Alcohol abuse is the most common cause of this condition. A condition of excess iron in the blood called hemochromatosis and cystic fibrosis are other known causes. The incidence of chronic pancreatitis is 2 cases per 10,000 individuals. Men are affected more often than women. Chronic pancreatitis is detected by reviewing the individual’s history. Samples of blood are taken to look for changes associated with this disease.
The most common symptom of chronic pancreatitis is pain. The pain is variable in its intensity. It may be low-grade, persistent pain with recurring acute attacks. The pain may be constant and boring. The back and abdomen are the sites of pain. Weight loss is another symptom. This is due to the malabsorption of fat. Large, foul-smelling, bulky stools called steatorrhea can also occur because of the inability to digest fat. There can be abdominal distention and fever may also be present.
There are two focuses of treatment. The first is the management of pain. The preferred treatment for the pain is non-narcotic pain relievers. Long-term narcotic use can lead to dependence and addiction. Referral to a pain specialist may be helpful. The second focus is replacing the digestive enzymes and insulin if they are no longer made in sufficient quantity by the pancreas. Pancreatic enzymes are available in tablet form. These are taken with meals and snacks. Insulin injections are used to control the blood sugar level. It may be necessary to give vitamin supplements because of an inability to digest fat-soluble vitamins including A, D, and K.
If the pain cannot be controlled, surgery is an option. In advanced cases, removal of all or part of the pancreas is an option.
The DOs
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When to Call Your Doctor
For More Information
National Digestive Diseases Information Clearinghouse
2 Information Way
Bethesda, MD 20892-3570
www.niddk.nih.gov
Derived from Patient Teaching Guide, © Mosby, Inc. All Rights Reserved
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